"Ventana is a global leader in companion diagnostics. Our HER2 diagnostics portfolio, including both the VENTANA IHC and INFORM HER2 Dual ISH assays, is the market leader in terms of automation, medical value and customer adoption," says Doug Ward, Vice President, Companion Diagnostics, Ventana Medical Systems, Inc. "We are working to enable the VENTANA HER2 (4B5) IHC companion diagnostic assay in all markets where Perjeta and Kadcyla are available for therapy, bringing this technology to physicians and patients worldwide." In addition to Roche, Ventana has worked with more than 45 bio-pharmaceutical partners over the past decade and is currently engaged in over 150 collaborative projects to develop and commercialize companion diagnostics globally. For more than a decade, Herceptin (trastuzumab), a HER2-directed therapy, has been approved by health authorities for people with HER2-positive breast cancer. To further help build on the progress made with Herceptin, Roche has recently introduced two additional HER2-directed therapies, Perjeta (pertuzumab) and Kadcyla (ado-trastuzumab emtansine). Perjeta (pertuzumab) is approved for use in combination with Herceptin (trastuzumab) and docetaxel chemotherapy in people with HER2-positive breast cancer that has spread to different parts of the body (metastatic) and who have not received anti-HER2 therapy or chemotherapy for metastatic disease. Kadcyla (ado-trastuzumab emtansine) is approved for the treatment of people with HER2-positive metastatic breast cancer (mBC) who have received prior treatment with Herceptin (trastuzumab) and a taxane chemotherapy. People should either have already been treated for their metastatic cancer or have had their early-stage cancer come back during or within six months after they completed a course of treatment following surgery. Herceptin is approved for the treatment of early-stage breast cancer that is Human Epidermal growth factor Receptor 2-positive (HER2+) and has spread into the lymph nodes, or is HER2+ and has not spread into the lymph nodes. If it has not spread into the lymph nodes, the cancer needs to be estrogen receptor/progesterone receptor (ER/PR)-negative or have one high risk feature.* Herceptin can be used in several different ways: As part of a treatment course including the chemotherapy drugs doxorubicin, cyclophosphamide, and either paclitaxel or docetaxel.
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Stomach (Gastric) Cancer Screening
Stomach cancer is the fourth most common cancer type worldwide. Knowledge is power; thus, everyone should learn about the risk factors for stomach cancer. Such knowledge could save lives. The American Cancer Society estimated that, last year alone, more than 10,000 Americans died from stomach cancer. Overall, 1 in 114 men and women are at a lifetime risk of developing stomach cancer. Signs and symptoms of stomach cancer can include the following: Loss of appetite Sense of fullness after eating small amounts of food Abdominal pain , usually above the navel area Heartburn, indigestion or ulcer-type symptoms Nausea and vomiting with or without blood Lifestyle behaviors considered to be risk factors for stomach cancer include: Smoking Diets rich in smoked, salted and pickled foods Diets low in fresh fruits and vegetables. Early detection is the key to surviving stomach cancer. Lifestyle changes can reduce the risk of stomach cancer and knowing ones family health history is equally important (some types of cancers have inherited cancer specifics). For more information on stomach cancer, including research, treatment options, education and more, please visit the No Stomach For Cancer website. This organization is involved in raising awareness and supporting efforts for education and treatment of stomach cancer.
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Stomach Cancer Awareness Month
There is no standard or routine screening test for stomach cancer. Upper endoscopy has been studied as a screening test to find stomach cancer at an early stage. Upper endoscopy is a procedure to look inside the esophagus, stomach, and duodenum (first part of the small intestine) to check for abnormal areas. An endoscope, a thin, tube-like instrument with a light and a lens for viewing, is passed through the mouth and down the throat into the esophagus. It may also have a tool to remove tissue to be checked under a microscope for signs of disease. Upper endoscopy. A thin, lighted tube is inserted through the mouth to look for abnormal areas in the esophagus, stomach, and first part of the small intestine. Some studies show that screening tests for stomach cancer, such as upper endoscopy, would not result in a lower death rate.
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Quite too often though, this motive to build the super ornate home demonstrates its self such as the construction of a fort that separates us from our ideals and what exactly which we actually wanted to accomplish. Our motives were to build something beautiful and ornate but we wind up creating something large and gaudy. If the designer isn't careful in their blending of treatments and trims, we find yourself designing something that was not really a reflection of ourselves, but of something that is from someone else's past ideas and not really what we had in mind at all.
The exact same may be said in regards to the motives that influence us who want to design an inferior house. Fortunately, it is not true to the exact same extent. Firstly, more regularly than not, we lack the money for the super elaborate. The materials we build our home from need to be found close available, and for the sake of economy, they should be inexpensive. This particular influence along with a lot of others of an identical nature force us towards the style of the smaller house which actually could be more intimate.
In American homes, especially small ones, we have learned to be inventive in order to make the house more personal in nature. Sixty percent of the homes integrated the United States follow the straightforward Ranch or ranchers pride design that includes a very self-explanatory layout and could be designed with economy in mind. The ranchers pride
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Nutrition News: Healthy eating app
Scaling up Nutrition (SUN) Civil Society Network Manager at Save the Children UK Claire Blanchard said in an interview in Lusaka that Dr Kaseba has emerged as a true champion of womens nutrition in Zambia. One of the things that have inspired me since I have been here is to see voices of nutrition champions such as the First Lady Dr Kaseba raising womens access to adequate and nutritious food as a priority, Ms Blanchard says. She added, As the Scaling up Nutrition Civil Society Network, we want to support more champions like the First Lady to continue raising awareness around the issue of under nutrition and over nutrition and also contribute to civil society advocacy efforts. Ms Blanchard said the Zambian government is showing great leadership in nutrition development but called for the momentum to be sustained in order to have long term effects and a more productive Zambia. Ms Blanchard said there is need to continue raising voices around issues affecting womens nutrition and household food security if Zambia is to tackle child malnutrition. She said nutrition has a low profile at national and household level despite statistics indicating that half of Zambians are not properly nourished. Obviously, nutrition is still not understood as a priority by everyone and this is the reason why every single stakeholder has a key role to play, the media is important by reaching out to every household and spreading messages that could easily be understandable, concrete actions that can be done at household level. Ms Blanchard said the Scaling up Nutrition movement believes that good nutrition is a human right For us, nutrition is a human right. The right nutrition can lead to more production nations with better educational achievement for children, more productive adults in later life. She said raising the status of women is key to addressing nutrition issues at household level. Women that are small entrepreneurs have the time to breast feed and give the right basis for their children to develop better in life and be active contributor to society. Ms Blanchard emphasized the need for a much more sustainable agriculture system which will have small holder farmers and producers at the centre and encourage access to a diverse diet and clean water and sanitation. Chronic malnutrition is a big problem in Zambia with half of Zambians not being properly nourished and 1 in 2 children stunted.
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The criteria are based on nutritional recommendations from the USDA and stress lean proteins, fruits and vegetables, whole grains and unsaturated fats. Entrees must have 750 calories or less, no more than 25 grams of fat and no more than 8 grams of saturated fat. Appetizers must have less than 250 calories, 8 grams of fat and 3 grams of saturated fat. Deep-fried items are entirely excluded, save for a garnish like wonton strips. "Healthy Dining Finder" also highlights low-sodium items for those with specific dietary requirements and identifies allergens and glutens. Once the app is downloaded, you can choose a restaurant and then find the healthiest menu options. Don't peel it When you remove the peel or skin from fruits and vegetables, you lose a lot of nutrition it's a concentrated source of fiber, vitamins, minerals and potentially beneficial phytochemicals.
The growth of online classifieds and free advertising
The rapid growth of Internet usage has augmented the necessity for entrepreneurs and service companies to post free ads, Classifieds campaigns online. Also, with the changing scenario and the increasing usage of the Internet classified ad programs are now designed essentially for web users. Also several classified ad sites now offer Used advertising site, Used ads, second-hand products to manage your competition produced by free classifieds advertising provided by other mediums. The biggest advantageous asset of free online classifieds is they've a higher viewer ship than that of classified ad that's been put into an area newspaper or a magazine.
The market for online classified advertising is increasing at an astounding rate and with websites vying for more users, so can be the opportunities free of charge classifieds advertising. Other mediums of free ad classifieds advertising give you a high readership too, but undoubtedly the reach of the Internet is certainly much wider.
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Advantages of online classified advertising
Online classified advertising has numerous advantages over a classified ad put into the standard print mediums. The main being that an online classified advertising program is easier and easily accessible, and in case there is free classifieds advertising online the huge benefits are numerous. Another advantageous asset of online advertising is that an individual gets the most recent and updated informative data on the classified ad sites.
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Designing a targeted ad campaign
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Extreme Sports and Funny Bloopers on At Your Leisure
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Like way up in the air. Then straight back down. by Rick Chandler | 8:49 pm, July 25th, 2013 Not the way they drew it up. Stunt double! The Fabulous, Sporty Life Of Lindsey Vonn: From Busted Knee To Tiger Woods British Open Date In 13 Photos by Eric Goldschein | 12:08 pm, July 16th, 2013 If you like sports, youd love to be Lindsey Vonn. Dating one of the worlds top athletes, training around the globe, playing all kinds of extreme sports and hanging out with dolphins? http://www.sportsgrid.com/category/extreme-sports-2/
Meet the thrill-seekers leading the charge for extreme air sports
The participant's voluntary decision to face the risk inherent in an extreme sport is not a complete bar to recovery, but rather results in a form of recovery based on comparative fault. Under comparative fault, the responsibility of both the participant and the sponsor or provider is relevant, and damages will be apportioned between the parties. What if the extreme sport participant signed a waiver of liability? Before an athlete competes in an extreme sporting event, the athlete will usually be asked to sign a liability waiver that contains language absolving the sponsor or provider of liability for its own negligent acts. This liability waiver, in turn, may bar an athlete from imposing liability on a sponsor or provider for any injuries the athlete may sustain as a result of a sponsor's or provider's negligence. In some states, if the participant suffers an injury as a result of the sponsor's/provider's negligence, despite the signed waiver, the sponsor/provider should not be able to escape liability, based on public policy, and comparative fault may apply. http://www.wesh.com/news/entertainment/extreme-sports-worth-the-legal-risk/-/11787862/23469790/-/10spoa9z/-/index.html
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Extreme Sport, Extreme Chic, Extreme Hype
Barang was joined by two other skydivers both foreigners who jumped seven times at a public display for the second annual Sea Festival in Kep province. According to the Cambodian Air Sports Federation (ASF), members of which conducted the jumps, it was almost certainly the first civilian jump in the Kingdom. ASF member Ansiau La Planeta, an ex-French special forces paratrooper who previously trained the Royal Cambodian Armed Forces airborne soldiers, said the jumps would hopefully be the beginning of a thriving skydiving culture for the Kingdom. We want to show that we can practise such sports with seriousness and safety, said La Planeta. Its extreme, sure, but less dangerous than driving a motorcycle in downtown Phnom Penh. ASF president Seang Teng said he wants to promote all air sports, which also encompass paragliding, paramotoring, hot air ballooning, aeromodelling, skydiving and ultralight flying. The weekends jumps attracted a crowd of onlookers, he added. http://www.phnompenhpost.com/7days/meet-thrill-seekers-leading-charge-extreme-air-sports
Extreme sports … worth the (legal) risk?
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But Studies In Humans Have Suggested That Removing The Original Cancer In The Breast May Increase Survival.
A traumatic brain injury occurs when the head violently impacts another object, or an object penetrates the skull, reaching the brain, according to the U.S. National Institute of Neurological Disorders and Stroke. War-related traumatic brain injuries are common. The use of improvised explosive devices (IEDs), rocket-propelled grenades and land mines in the Iraq and Afghanistan wars are the main contributors to deployment-related traumatic brain injuries today. More than half are caused by IEDs, the study authors noted. Previous research has suggested that experiencing a traumatic brain injury increases the risk of PTSD. The disorder can occur after someone experiences a traumatic event. Such events put the body and mind in a high-alert state because you feel that you or someone else is in danger.
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Chemo for Advanced Breast Cancer Might Be Enough
Rajendra Badwe, head of the surgical breast unit at Tata Memorial Hospital in Mumbai, India. It didn't seem to matter if patients were young or old, if their cancer was hormone receptor positive or negative, or if they had a few sites of spreading cancer or a lot. Surgery didn't prolong their lives. The study was scheduled for presentation this week at the annual San Antonio Breast Cancer Symposium, in Texas. The results aren't shocking, since experiments in animals performed more than 30 years ago suggested that cutting out the primary tumor only egged on cancer at the secondary sites. But studies in humans have suggested that removing the original cancer in the breast may increase survival.
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While The Findings Suggest That Music Lessons Won't Improve A Child's School Grades, Music Education Is Still Important, According To Mehr.
Will Music Make Your Child Smarter?
Such Events Put The Body And Mind In A High-alert State Because You Feel That You Or Someone Else Is In Danger.
Again, the researchers found that music lessons did not provide any brain benefit, according to the study published Dec. 11 in the journal PLoS One. While the findings suggest that music lessons won't improve a child's school grades, music education is still important, according to Mehr. "There's a compelling case to be made for teaching music that has nothing to do with extrinsic benefits. We don't teach kids Shakespeare because we think it will help them do better on the SATs, we do it because we believe Shakespeare is important," he said. "Music is an ancient, uniquely human activity -- the oldest flutes that have been dug up are 40,000 years old, and human song long preceded that," Mehr noted. "Every single culture in the world has music, including music for children.
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